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NAD; 4 More Reasons to take NMN

take NMN to raise NAD

NAD or Nicotinamide Adenine Dinucleotide to give it its full name is present in nearly all of our li

Nicotinamide Mononucleotide (NMN) is used to raise our NAD, our NAD levels drop as we age, so by taking NMN, in theory, we can replace our depleted NAD levels.  

NAD or Nicotinamide Adenine Dinucleotide to give it its full name is found in virtually all our living cells and is essential for sustaining life. 

NAD and inflammation
NAD protects against hemical stress, inflammation, DNA damage

A key aspect of NAD is its role in protecting against aging, including moderating chemical stress, inflammation, DNA damage, and deteriorating mitochondria, all conditions associated with aging, NMN may be a way of addressing these issues. 

While a decline in NAD+ levels may reduce lifespan, so restoring NAD by taking NMN is now seen as a potential way to support longevity and combat the diseases of aging too. 

energy intensive enzymes and NAD

NAD and ATP
the electron transport chain

A key feature of aging is the loss of energy at the cellular level, resulting in diminished ATP (adenosine triphosphate) and insufficient fuel to energize the body.

One reason for loss of energy is a reduction in the effectiveness of the electron transport chain, the main way in which we extract energy from food. Disorders and diseases ranging from obesity to diabetes to bone loss have been associated with the degradation of this pathway.

Restoring the electron transport chain by upping NAD levels may be an effective way of promoting the crucial enzymes involved in sustaining youthful cell function. This may then help fight biological decline and protect against age-related disease.

chromosome stability and NAD

Our chromosomes and NAD
Stable chromosomes require adequate levels of  NAD

Our chromosomes are complex structures that encapsulate our DNA.  Access to DNA for reading genetic instructions requires bio-chemical control to ensure every gene functions in the way it was designed.

Like any complex organization, chromosomes can become unstable. This can then trigger errors in the way our genes are expressed, which may lead to unwanted changes in cell function.  Aging is accelerated when our chromosome do not function as intended. Stable chromosomes require adequate levels of  NAD to function correctly. 

neurotransmitters and NAD 

Neurotransmitters and NAD
NAD meets all criteria for a neurotransmitter

Neurotransmitters are elements that allow neuro-transmission.  This chemical element transmits signals across our synapses and also help regulate bodily functions such as mood and appetite.

NAD meets all criteria for a neurotransmitter, evidence for NAD+’s neurotransmitter function has now been found in blood vessel, smooth muscles and in the brain.

sirtuin activation and NAD

Sirtuins and NAD
NAD is required for some sirtuins to function

Sirtuins are major regulators of cellular aging, they influence key functions such as DNA repair and inflammatory responses. They also influence whether cells either replicate or die a planned death (apoptosis).

Compounds that activate sirtuins are in high demand as biological “fountains of youth.”  Supplements like Resveratrol and quercetin have also been evaluated as promising sirtuin activators.

NAD is required for some sirtuins to function; sirtuin activity has been linked to fighting cardiovascular disease and stabilizing brain function, but Sirtuins cannot function effectively without the right amount of NAD.

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conclusion

As we age our NAD levels decrease, NAD is essential to many functions such as cellular energy utilization, immune-cell signaling and DNA repair.  By boosting our ever diminishing NAD levels with an NAD Booster such as NMN, we can hopefully restore our NAD to youthful levels.