Table of Contents
why raise our nad?
There are many are many reasons to take NMN, one is to raise our NAD. to give it its full name is present in nearly all of our living cells, NAD+ is essential for sustaining life. Unfortunately our NAD levels decline radically with age; this creates an energy deficit that decreases our body’s ability to maintain effective biological functions.
NAD is biologically unstable, which makes it unsuitable for oral supplementation. Fortunately, it is easy to restore our cellular NAD levels using , which converts to NAD when it is in the cell.
how much does our nad drop as we age?
To give you an idea how our ; by the age fifty a typical person may have only half the cellular NAD+ they once had in their youth and by the age eighty, NAD+ levels drop to between 1% to 10% of those enjoyed in our youth. This is one of the key reasons to take NMN.
An important feature of NAD+ is its dual role in protecting against factors that age us. This includes alleviating chemical stress, inflammation, DNA damage and deteriorating mitochondria, all conditions associated with aging.
So, a decline in NAD+ levels may , so restoring NAD+ is increasingly being viewed as a cutting-edge tool to promote longevity and a way to combat the diseases of aging too. So, alleviating chemical stress, inflammation, DNA damage and deteriorating mitochondria are all good reasons to take NMN.
Let’s look at ways in which having high levels of NAD benefits us.
restore cellular energy with nad
NAD+ is required for accurate cellular energy utilization. Our ; this creates an energy shortfall that diminishes our body’s ability to retain efficient functions at the cellular level. Unfortunately NAD is unstable and cannot be used as an oral supplement, but NMN an NAD precursor is capable of restoring cellular NAD+ levels, another of the reasons to take NMN.
Studies have shown that NAD supplementation can and improve many of the metabolic defects common to the aging process, including obesity, diabetes, cardiovascular disease and neurodegenerative conditions.
nad may contribute to longer telomeres
Telomeres are elements of repetitive DNA that seal the ends of our chromosomes. every time a cell replicates itself. Once telomeres reach a critically short length, cell renewal practically stops, this leads to the accelerated aging or death of the cell. Telomere shortening is both a marker of cellular aging and a predictor of shortened lifespan.
NAD+ is required for the ; they contribute to longevity and specifically to maintaining the length of critical telomeres. Maintaining longer telomeres is another one of the reasons to take NMN.
Other compounds, such as resveratrol, may activate the sirtuins and contribute to extending lifespan, but evidence suggests (10).
Taking NMN as a supplement is not the magic bullet for longevity. and weight loss have been reliably shown to be effective at telomere lengthening.
nad promotes dna repair
Even though DNA is protected by its chromosomal sheath, it is extremely vulnerable to injury. This can lead to broken DNA strands and mutations in essential genes. Constant DNA damage contributes to the aging process and can result in specific lifespan-shortening diseases such as and poor immune function.
When DNA is damaged, it activates an enzyme known as PARP-1. PARP-1 carries out DNA essential repair within our cells. To carry out its function PARP-1 consumes colossal amounts of NAD+, as the NAD+ is depleted the ability of PARP-1 to repair DNA is significantly hampered. Therefore another one of the reasons to take NMN is to activate the PARP-1 enzyme to repair our DNA.
Improving may slow cellular aging, it may also reduce the resolve of cancer-causing mutations and play an important role in preventing inflammatory conditions such as atherosclerosis.
nad modulates immune-cell signaling
As we age our immune cells begin to lose concentration, some become overactive and contribute to , while others slow-down and increase our risk of infection.
The process, called immune-senescence is closely related to mitochondrial function and energy stability, both of which depend on . One of the most important reasons to take NMN is to ensure that our mitochondrial function is operating as efficiently as possible.
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conclusion
There are many reasons to take NMN, here I have covered only 4. As we age our NAD levels decrease; NAD is essential for many of our bodily functions such as cellular energy utilization, immune-cell signaling and DNA repair. By boosting our ever diminishing NAD levels with an NAD Booster such as NMN, we can hopefully restore our NAD to youthful levels.